2fos | pdb_00002fos

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File:2fos.png

Template:STRUCTURE 2fos

Human Carbonic Anhydrase II complexed with two-prong inhibitors

Template:ABSTRACT PUBMED 16506782

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2FOS is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Jude KM, Banerjee AL, Haldar MK, Manokaran S, Roy B, Mallik S, Srivastava DK, Christianson DW. Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity. J Am Chem Soc. 2006 Mar 8;128(9):3011-8. PMID:16506782 doi:https://dx.doi.org/10.1021/ja057257n

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