2hho | pdb_00002hho

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Template:STRUCTURE 2hho

File:2hho.png

NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16762918

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2HHO is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain. J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:16762918 doi:https://dx.doi.org/10.1074/jbc.M602691200

Page seeded by OCA on Tue Feb 17 15:20:08 2009

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OCA

[1] Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain. J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:16762918 doi:https://dx.doi.org/10.1074/jbc.M602691200

2hho | pdb_00002hho

Contents

NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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