2viz | pdb_00002viz
From Proteopedia
HUMAN BACE-1 IN COMPLEX WITH N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(2-OXO-1-PYRROLIDINYL)-5-(PROPYLOXY) BENZAMIDE
About this Structure
2VIZ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Clarke B, Demont E, Dingwall C, Dunsdon R, Faller A, Hawkins J, Hussain I, MacPherson D, Maile G, Matico R, Milner P, Mosley J, Naylor A, O'Brien A, Redshaw S, Riddell D, Rowland P, Soleil V, Smith KJ, Stanway S, Stemp G, Sweitzer S, Theobald P, Vesey D, Walter DS, Ward J, Wayne G. BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs). Bioorg Med Chem Lett. 2008 Feb 1;18(3):1011-6. Epub 2007 Dec 15. PMID:18171614 doi:https://dx.doi.org/10.1016/j.bmcl.2007.12.017
Page seeded by OCA on Tue Feb 17 15:30:56 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Brien, A O.
- Clarke, B.
- Demont, E.
- Dingwall, C.
- Dunsdon, R.
- Faller, A.
- Hawkins, J.
- Hussain, I.
- Macpherson, D.
- Maile, G.
- Matico, R.
- Milner, P.
- Mosley, J.
- Naylor, A.
- Redshaw, S.
- Riddell, D.
- Rowland, P.
- Smith, K.
- Soleil, V.
- Stanway, S.
- Stemp, G.
- Sweitzer, S.
- Theobald, P.
- Vesey, D.
- Walter, D S.
- Ward, J.
- Wayne, G.
- Alternative splicing
- Asp-2
- Aspartyl protease
- Bace-1
- Beta-secretase
- Beta-site app cleaving enzyme
- Glycoprotein
- Hydrolase
- Memapsin-2
- Membrane
- Protease
- Transmembrane
- Zymogen
