3b9f | pdb_00003b9f
From Proteopedia
1.6 A structure of the PCI-thrombin-heparin complex
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3B9F is a 3 chains structure of sequences from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li W, Adams TE, Nangalia J, Esmon CT, Huntington JA. Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4661-6. Epub 2008 Mar 24. PMID:18362344
Page seeded by OCA on Tue Feb 17 15:51:49 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Bos taurus
- Homo sapiens
- Thrombin
- Adams, T E.
- Huntington, J A.
- Li, W.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydrolase/hydrolase inhibitor complex
- Kringle
- Michaelis complex
- Polymorphism
- Protease
- Secreted
- Serine protease
- Zymogen