2iko | pdb_00002iko
From Proteopedia
Template:ABSTRACT PUBMED 17113558
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| 2iko, resolution 1.90Å (default scene) | |||||||||||||
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| Ligands: | 7IG | ||||||||||||
| Gene: | REN (Homo sapiens) | ||||||||||||
| Activity: | Renin, with EC number 3.4.23.15 | ||||||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal Structure of Human Renin Complexed with Inhibitor
Disease
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[179820], Hyperproreninemia OMIM:[179820]
About this Structure
2IKO is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sarver RW, Peevers J, Cody WL, Ciske FL, Dyer J, Emerson SD, Hagadorn JC, Holsworth DD, Jalaie M, Kaufman M, Mastronardi M, McConnell P, Powell NA, Quin J 3rd, Van Huis CA, Zhang E, Mochalkin I. Binding thermodynamics of substituted diaminopyrimidine renin inhibitors. Anal Biochem. 2007 Jan 1;360(1):30-40. Epub 2006 Oct 30. PMID:17113558 doi:https://dx.doi.org/10.1016/j.ab.2006.10.017
Page seeded by OCA on Tue Feb 17 15:54:58 2009
