2gv7 | pdb_00002gv7

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Template:STRUCTURE 2gv7

File:2gv7.png

Structure of Matriptase in Complex with Inhibitor CJ-672

Template:ABSTRACT PUBMED 16821772

Disease

Known disease associated with this structure: Ichthyosis with hypotrichosis OMIM:[606797]

About this Structure

2GV7 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Steinmetzer T, Schweinitz A, Sturzebecher A, Donnecke D, Uhland K, Schuster O, Steinmetzer P, Muller F, Friedrich R, Than ME, Bode W, Sturzebecher J. Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. J Med Chem. 2006 Jul 13;49(14):4116-26. PMID:16821772 doi:10.1021/jm051272l

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