3bea | pdb_00003bea

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File:3bea.png

Template:STRUCTURE 3bea

cFMS tyrosine kinase (tie2 KID) in complex with a pyrimidinopyridone inhibitor

Template:ABSTRACT PUBMED 18342505

About this Structure

3BEA is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Huang H, Hutta DA, Hu H, DesJarlais RL, Schubert C, Petrounia IP, Chaikin MA, Manthey CL, Player MR. Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2355-61. Epub 2008 Mar 4. PMID:18342505 doi:10.1016/j.bmcl.2008.02.070

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