2ia6 | pdb_00002ia6

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Template:ABSTRACT PUBMED 17848527

File:2ia6.png


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2ia6, resolution 2.50Å (default scene)
Ligands: ATP, BAP, CA, EDO, GOL, PO4
Gene: dbh, dpo4 (Sulfolobus solfataricus P2)
Activity: DNA-directed DNA polymerase, with EC number 2.7.7.7
Related: 2ibk
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Bypass of Major Benzopyrene-dG Adduct by Y-Family DNA Polymerase with Unique Structural Gap

About this Structure

2IA6 is a 6 chains structure of sequences from Sulfolobus solfataricus p2. Full crystallographic information is available from OCA.

Reference

  1. Bauer J, Xing G, Yagi H, Sayer JM, Jerina DM, Ling H. A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14905-10. Epub 2007 Sep 11. PMID:17848527

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