2k05 | pdb_00002k05
From Proteopedia
Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21
Disease
Known disease associated with this structure: Myelokathexis, isolated OMIM:[162643], WHIM syndrome OMIM:[162643]
About this Structure
2K05 is a 4 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.
Reference
- Veldkamp CT, Seibert C, Peterson FC, De la Cruz NB, Haugner JC 3rd, Basnet H, Sakmar TP, Volkman BF. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci Signal. 2008 Sep 16;1(37):ra4. PMID:18799424 doi:1/37/ra4
Page seeded by OCA on Tue Feb 17 17:34:33 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Peterson, F C.
- Veldkamp, C T.
- Volkman, B F.
- Alternative splicing
- Chemokine
- Chemotaxis
- Cxcl12
- Cxcr4
- Cytokine
- G-protein coupled receptor
- Glycoprotein
- Growth factor
- Host-virus interaction
- Locked dimer
- Membrane
- Receptor
- Sdf1-alpha
- Secreted
- Stromal cell derived factor-1
- Sulfation
- Sulfotyrosine
- Transducer
- Transmembrane
