2fz8 | pdb_00002fz8

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File:2fz8.png

Template:STRUCTURE 2fz8

Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).

Template:ABSTRACT PUBMED 16952371

About this Structure

2FZ8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G. Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:16952371 doi:https://dx.doi.org/10.1016/j.jmb.2006.08.011

Page seeded by OCA on Tue Feb 17 17:44:22 2009

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