3bjc | pdb_00003bjc
From Proteopedia
Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor
Template:ABSTRACT PUBMED 18346713
About this Structure
3BJC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chen G, Wang H, Robinson H, Cai J, Wan Y, Ke H. An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies. Biochem Pharmacol. 2008 May 1;75(9):1717-28. Epub 2008 Feb 12. PMID:18346713 doi:10.1016/j.bcp.2008.01.019
Page seeded by OCA on Tue Feb 17 18:41:44 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- 3',5'-cyclic-GMP phosphodiesterase
- Homo sapiens
- Cai, J.
- Chen, G.
- Howard, R.
- Ke, H.
- Wan, Y.
- Wang, H.
- Allosteric enzyme
- Alternative splicing
- Cgmp
- Cgmp-binding
- Crystal structure
- Erectile dysfunction
- Hydrolase
- Inhibitor design
- Magnesium
- Metal-binding
- Nucleotide-binding
- Pde5
- Phosphoprotein
- Polymorphism
- Zinc
