1u0n | pdb_00001u0n
From Proteopedia
The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex
Disease
Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[606672], Bernard-Soulier syndrome, type A OMIM:[606672], von Willebrand disease, platelet-type OMIM:[606672], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[606672]
About this Structure
1U0N is a 4 chains structure of sequences from Bothrops jararaca and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fukuda K, Doggett T, Laurenzi IJ, Liddington RC, Diacovo TG. The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation. Nat Struct Mol Biol. 2005 Feb;12(2):152-9. Epub 2005 Jan 16. PMID:15665869 doi:10.1038/nsmb892
Page seeded by OCA on Tue Feb 17 20:17:14 2009
