2ib9 | pdb_00002ib9

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Template:STRUCTURE 2ib9

File:2ib9.png

Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function

Template:ABSTRACT PUBMED 17371050

Disease

Known disease associated with this structure: Alpha-methylacetoacetic aciduria OMIM:[607809]

About this Structure

2IB9 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Haapalainen AM, Merilainen G, Pirila PL, Kondo N, Fukao T, Wierenga RK. Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function. Biochemistry. 2007 Apr 10;46(14):4305-21. Epub 2007 Mar 20. PMID:17371050 doi:10.1021/bi6026192

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