2qcf | pdb_00002qcf

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File:2qcf.png

Template:STRUCTURE 2qcf

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP

Template:ABSTRACT PUBMED 18184586

Disease

Known disease associated with this structure: Oroticaciduria OMIM:[258900]

About this Structure

2QCF is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Wittmann JG, Heinrich D, Gasow K, Frey A, Diederichsen U, Rudolph MG. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure. 2008 Jan;16(1):82-92. PMID:18184586 doi:https://dx.doi.org/10.1016/j.str.2007.10.020

Page seeded by OCA on Tue Feb 17 21:01:40 2009

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OCA

[1] Wittmann JG, Heinrich D, Gasow K, Frey A, Diederichsen U, Rudolph MG. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure. 2008 Jan;16(1):82-92. PMID:18184586 doi:https://dx.doi.org/10.1016/j.str.2007.10.020

2qcf | pdb_00002qcf

Contents

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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