2oqv | pdb_00002oqv

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Template:STRUCTURE 2oqv

File:2oqv.png

Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine

Template:ABSTRACT PUBMED 17367123

About this Structure

2OQV is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Pei Z, Li X, von Geldern TW, Longenecker K, Pireh D, Stewart KD, Backes BJ, Lai C, Lubben TH, Ballaron SJ, Beno DW, Kempf-Grote AJ, Sham HL, Trevillyan JM. Discovery and structure-activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors. J Med Chem. 2007 Apr 19;50(8):1983-7. Epub 2007 Mar 17. PMID:17367123 doi:10.1021/jm061436d

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