2iwx | pdb_00002iwx

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Template:STRUCTURE 2iwx

File:2iwx.png

ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.

Template:ABSTRACT PUBMED 17114002

About this Structure

2IWX is a 1 chain structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol. Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002 doi:10.1016/j.chembiol.2006.09.015

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OCA

[1] Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol. Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002 doi:10.1016/j.chembiol.2006.09.015

2iwx | pdb_00002iwx

ANALOGUES OF RADICICOL BOUND TO THE ATP-BINDING SITE OF HSP90.

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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