1twx | pdb_00001twx

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File:1twx.png

Template:STRUCTURE 1twx

Crystal structure of the thrombin mutant D221A/D222K

Template:ABSTRACT PUBMED 15572256

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

1TWX is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Pineda AO, Zhang E, Guinto ER, Savvides SN, Tulinsky A, Di Cera E. Crystal structure of the thrombin mutant D221A/D222K: the Asp222:Arg187 ion-pair stabilizes the fast form. Biophys Chem. 2004 Dec 20;112(2-3):253-6. PMID:15572256 doi:https://dx.doi.org/10.1016/j.bpc.2004.07.027

Page seeded by OCA on Tue Feb 17 22:01:39 2009

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