3cyf | pdb_00003cyf

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Template:STRUCTURE 3cyf

File:3cyf.png

Crystal Structure of E18N DJ-1

Template:ABSTRACT PUBMED 18570440

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis-Parkinsonism/dementia complex 2 OMIM:[602533], Parkinson disease 7, autosomal recessive early-onset OMIM:[602533]

About this Structure

3CYF is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Witt AC, Lakshminarasimhan M, Remington BC, Hasim S, Pozharski E, Wilson MA. Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry. 2008 Jul 15;47(28):7430-40. Epub 2008 Jun 21. PMID:18570440 doi:https://dx.doi.org/10.1021/bi800282d

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