2b4c | pdb_00002b4c

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File:2b4c.png

Template:STRUCTURE 2b4c

Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody

Template:ABSTRACT PUBMED 16284180

Disease

Known disease associated with this structure: CD4 lymphocyte deficiency OMIM:[186940], Lupus erythematosus, susceptibility to OMIM:[186940]

About this Structure

2B4C is a 4 chains structure of sequences from Homo sapiens and Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, Stanfield RL, Dimitrov DS, Korber B, Sodroski J, Wilson IA, Wyatt R, Kwong PD. Structure of a V3-containing HIV-1 gp120 core. Science. 2005 Nov 11;310(5750):1025-8. PMID:16284180 doi:https://dx.doi.org/310/5750/1025

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