2bio | pdb_00002bio
From Proteopedia
HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-N239Y-R249S-N268D
Template:ABSTRACT PUBMED 15703170
About this Structure
2BIO is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR. Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations. J Biol Chem. 2005 Apr 22;280(16):16030-7. Epub 2005 Feb 9. PMID:15703170 doi:https://dx.doi.org/10.1074/jbc.M500179200
Page seeded by OCA on Wed Feb 18 02:02:14 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Fersht, A R.
- Joerger, A C.
- 3d-structure
- Activator
- Anti-oncogene
- Apoptosis
- Disease mutation
- Dna-binding
- Dna-binding protein
- Li-fraumeni syndrome
- Nuclear protein
- P53 dna-binding domain
- Phosphorylation
- Polymorphism
- Second-site suppressor mutation
- Superstable mutant
- Transcription regulation
- Tumor suppressor
