2qy0 | pdb_00002qy0
From Proteopedia
Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts
Disease
Known disease associated with this structure: C1r/C1s deficiency, combined OMIM:[216950]
About this Structure
2QY0 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kardos J, Harmat V, Pallo A, Barabas O, Szilagyi K, Graf L, Naray-Szabo G, Goto Y, Zavodszky P, Gal P. Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r. Mol Immunol. 2008 Mar;45(6):1752-60. Epub 2007 Nov 9. PMID:17996945 doi:10.1016/j.molimm.2007.09.031
Page seeded by OCA on Wed Feb 18 02:34:44 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Complement subcomponent C1r
- Homo sapiens
- Barabas, O.
- Gal, P.
- Goto, Y.
- Graf, L.
- Harmat, V.
- Kardos, J.
- Naray-Szabo, G.
- Pallo, A.
- Szilagyi, K.
- Zavodszky, P.
- Beta barrel
- Complement
- Complement pathway
- Egf-like domain
- Glycoprotein
- Hydrolase
- Hydroxylation
- Immune response
- Innate immunity
- Phosphorylation
- Polymorphism
- Serine protease
- Sushi
