2hnc | pdb_00002hnc

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File:2hnc.png

Template:STRUCTURE 2hnc

Crystal structure of the human carbonic anhydrase II in complex with the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.

Template:ABSTRACT PUBMED 17000110

About this Structure

2HNC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfona mide to human isoform II. Bioorg Med Chem Lett. 2006 Dec 15;16(24):6204-8. Epub 2006 Sep 26. PMID:17000110 doi:10.1016/j.bmcl.2006.09.022

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