2r0o | pdb_00002r0o

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File:2r0o.png

Template:STRUCTURE 2r0o

Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)

Template:ABSTRACT PUBMED 18164029

Disease

Known disease associated with this structure: Glomerulosclerosis, focal segmental, 1 OMIM:[604638]

About this Structure

2R0O is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lee SH, Weins A, Hayes DB, Pollak MR, Dominguez R. Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis. J Mol Biol. 2008 Feb 15;376(2):317-24. Epub 2007 Dec 4. PMID:18164029 doi:10.1016/j.jmb.2007.11.084

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