2f54 | pdb_00002f54

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File:2f54.png

Template:STRUCTURE 2f54

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity

Template:ABSTRACT PUBMED 16600963

Disease

Known disease associated with this structure: Hypoproteinemia, hypercatabolic OMIM:[109700]

About this Structure

2F54 is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Dunn SM, Rizkallah PJ, Baston E, Mahon T, Cameron B, Moysey R, Gao F, Sami M, Boulter J, Li Y, Jakobsen BK. Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. Protein Sci. 2006 Apr;15(4):710-21. PMID:16600963 doi:15/4/710

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