2qce | pdb_00002qce

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Template:STRUCTURE 2qce

File:2qce.png

Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride

Template:ABSTRACT PUBMED 18184586

Disease

Known disease associated with this structure: Oroticaciduria OMIM:[258900]

About this Structure

2QCE is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wittmann JG, Heinrich D, Gasow K, Frey A, Diederichsen U, Rudolph MG. Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure. 2008 Jan;16(1):82-92. PMID:18184586 doi:https://dx.doi.org/10.1016/j.str.2007.10.020

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