2erj | pdb_00002erj
From Proteopedia
Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2
Disease
Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[147730], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[147730], Combined immunodeficiency, X-linked, moderate OMIM:[308380], Severe combined immunodeficiency, X-linked OMIM:[308380], Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]
About this Structure
2ERJ is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:16477002
Page seeded by OCA on Wed Feb 18 06:00:57 2009
