1zsb | pdb_00001zsb
From Proteopedia
CARBONIC ANHYDRASE II MUTANT E117Q, TRANSITION STATE ANALOGUE ACETAZOLAMIDE
Disease
Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]
About this Structure
1ZSB is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huang, CC, Lesburg CA, Kiefer LL, Fierke CA, Christianson DW. Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry. 1996 Mar 19;35(11):3439-46. PMID:8639494 doi:10.1021/bi9526692
Page seeded by OCA on Wed Feb 18 06:08:24 2009
