2vqo | pdb_00002vqo
From Proteopedia
STRUCTURE OF HDAC4 CATALYTIC DOMAIN WITH A GAIN-OF-FUNCTION MUATION BOUND TO A TRIFLUOROMETHYLKETONE INHBITOR
About this Structure
2VQO is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bottomley MJ, Lo Surdo P, Di Giovine P, Cirillo A, Scarpelli R, Ferrigno F, Jones P, Neddermann P, De Francesco R, Steinkuhler C, Gallinari P, Carfi A. Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain. J Biol Chem. 2008 Sep 26;283(39):26694-704. Epub 2008 Jul 8. PMID:18614528 doi:https://dx.doi.org/10.1074/jbc.M803514200
Page seeded by OCA on Wed Feb 18 06:23:54 2009
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Categories:
- Pages with broken file links
- Homo sapiens
- Bottomley, M J.
- Carfi, A.
- Cirillo, A.
- Ferrigno, F.
- Francesco, R De.
- Gallinari, P.
- Giovine, P Di.
- Jones, P.
- Neddermann, P.
- Scarpelli, R.
- Steinkuhler, C.
- Surdo, P Lo.
- Chromatin
- Chromatin regulator
- Coiled coil
- Cytoplasm
- Hdac
- Hdaci
- Histone deacetylase
- Hydrolase
- Inhibitor
- Nucleus
- Phosphoprotein
- Polymorphism
- Repressor
- Transcription
- Transcription regulation
- Ubl conjugation
- Zinc