3c6t | pdb_00003c6t
From Proteopedia
Crystal Structure of HIV Reverse Transcriptase in complex with inhibitor 14
About this Structure
3C6T is a 2 chains structure of sequences from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.
Reference
- Tucker TJ, Saggar S, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Bioorg Med Chem Lett. 2008 May 1;18(9):2959-66. Epub 2008 Mar 25. PMID:18396399 doi:10.1016/j.bmcl.2008.03.064
Page seeded by OCA on Wed Feb 18 06:48:02 2009
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Categories:
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- Hiv-1 m:b hxb2r
- Prasad, S.
- Yan, Y.
- Aid
- Aspartyl protease
- Capsid maturation
- Capsid protein
- Cytoplasm
- Dna integration
- Dna recombination
- Dna-directed dna polymerase
- Endonuclease
- Hiv-1 reverse transcriptase
- Host-virus interaction
- Hydrolase
- Lipoprotein
- Magnesium
- Membrane
- Metal-binding
- Multifunctional enzyme
- Myristate
- Non-nucleoside inhibition
- Nuclease
- Nucleotidyltransferase
- Nucleotidyltrasferase
- Nucleus
- Phosphoprotein
- Protease
- Rna-binding
- Rna-directed dna polymerase
- Transferase
- Viral nucleoprotein
- Virion
- Zinc
- Zinc-finger