3c6t | pdb_00003c6t

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Template:STRUCTURE 3c6t

File:3c6t.png

Crystal Structure of HIV Reverse Transcriptase in complex with inhibitor 14

Template:ABSTRACT PUBMED 18396399

About this Structure

3C6T is a 2 chains structure of sequences from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

Reference

  1. Tucker TJ, Saggar S, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Bioorg Med Chem Lett. 2008 May 1;18(9):2959-66. Epub 2008 Mar 25. PMID:18396399 doi:10.1016/j.bmcl.2008.03.064

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