2hk5 | pdb_00002hk5

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Template:STRUCTURE 2hk5

File:2hk5.png

Hck Kinase in Complex with Lck targetted Inhibitor PG-1009247

Template:ABSTRACT PUBMED 16997556

About this Structure

2HK5 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sabat M, VanRens JC, Laufersweiler MJ, Brugel TA, Maier J, Golebiowski A, De B, Easwaran V, Hsieh LC, Walter RL, Mekel MJ, Evdokimov A, Janusz MJ. The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck). Bioorg Med Chem Lett. 2006 Dec 1;16(23):5973-7. Epub 2006 Sep 25. PMID:16997556 doi:10.1016/j.bmcl.2006.08.132

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