3coh | pdb_00003coh

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File:3coh.jpg

Template:STRUCTURE 3coh

Crystal structure of Aurora-A in complex with a pentacyclic inhibitor

Template:ABSTRACT PUBMED 18630890

About this Structure

3COH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Rawson TE, Ruth M, Blackwood E, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Georges GJ, Goller B, Halladay J, Hunsaker T, Kleinheinz T, Krell HW, Li J, Liang J, Limberg A, McNutt A, Moffat J, Phillips G, Ran Y, Safina B, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhou A, Zhu BY, Ruger P, Cochran AG. A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability. J Med Chem. 2008 Aug 14;51(15):4465-75. Epub 2008 Jul 17. PMID:18630890 doi:10.1021/jm800052b

Page seeded by OCA on Wed Feb 18 09:07:32 2009

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OCA

[1] Rawson TE, Ruth M, Blackwood E, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Georges GJ, Goller B, Halladay J, Hunsaker T, Kleinheinz T, Krell HW, Li J, Liang J, Limberg A, McNutt A, Moffat J, Phillips G, Ran Y, Safina B, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhou A, Zhu BY, Ruger P, Cochran AG. A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability. J Med Chem. 2008 Aug 14;51(15):4465-75. Epub 2008 Jul 17. PMID:18630890 doi:10.1021/jm800052b

3coh | pdb_00003coh

Crystal structure of Aurora-A in complex with a pentacyclic inhibitor

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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