3bel | pdb_00003bel
From Proteopedia
X-ray structure of EGFR in complex with oxime inhibitor
About this Structure
3BEL is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xu G, Searle LL, Hughes TV, Beck AK, Connolly PJ, Abad MC, Neeper MP, Struble GT, Springer BA, Emanuel SL, Gruninger RH, Pandey N, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Greenberger LM. Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3495-9. Epub 2008 May 10. PMID:18508264 doi:https://dx.doi.org/10.1016/j.bmcl.2008.05.024
Page seeded by OCA on Wed Feb 18 09:07:38 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Abad, M C.
- Connolly, P J.
- Gaul, M D.
- Neeper, M P.
- Struble, G T.
- Xu, G.
- Alternative splicing
- Anti-oncogene
- Atp-binding
- Cell cycle
- Disease mutation
- Glycoprotein
- Kinase domain
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Receptor
- Secreted
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Ubl conjugation
