2g26 | pdb_00002g26

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Template:STRUCTURE 2g26

File:2g26.png

Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring

Template:ABSTRACT PUBMED 16480874

Disease

Known disease associated with this structure: Renal tubular dysgenesis OMIM:[179820], Hyperproreninemia OMIM:[179820]

About this Structure

2G26 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Holsworth DD, Cai C, Cheng XM, Cody WL, Downing DM, Erasga N, Lee C, Powell NA, Edmunds JJ, Stier M, Jalaie M, Zhang E, McConnell P, Ryan MJ, Bryant J, Li T, Kasani A, Hall E, Subedi R, Rahim M, Maiti S. Ketopiperazine-based renin inhibitors: optimization of the "C" ring. Bioorg Med Chem Lett. 2006 May 1;16(9):2500-4. Epub 2006 Feb 15. PMID:16480874 doi:https://dx.doi.org/10.1016/j.bmcl.2006.01.084

Page seeded by OCA on Wed Feb 18 09:21:33 2009

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OCA

[1] Holsworth DD, Cai C, Cheng XM, Cody WL, Downing DM, Erasga N, Lee C, Powell NA, Edmunds JJ, Stier M, Jalaie M, Zhang E, McConnell P, Ryan MJ, Bryant J, Li T, Kasani A, Hall E, Subedi R, Rahim M, Maiti S. Ketopiperazine-based renin inhibitors: optimization of the "C" ring. Bioorg Med Chem Lett. 2006 May 1;16(9):2500-4. Epub 2006 Feb 15. PMID:16480874 doi:https://dx.doi.org/10.1016/j.bmcl.2006.01.084

2g26 | pdb_00002g26

Contents

Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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