2ano | pdb_00002ano

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Template:STRUCTURE 2ano

File:2ano.png

Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17

Template:ABSTRACT PUBMED 17125251

About this Structure

2ANO is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Summerfield RL, Daigle DM, Mayer S, Mallik D, Hughes DW, Jackson SG, Sulek M, Organ MG, Brown ED, Junop MS. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. J Med Chem. 2006 Nov 30;49(24):6977-86. PMID:17125251 doi:10.1021/jm060570v

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