2zb2 | pdb_00002zb2
From Proteopedia
Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide
Template:ABSTRACT PUBMED 18434170
Disease
Known disease associated with this structure: Glycogen storage disease VI OMIM:[232700]
About this Structure
2ZB2 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Bioorg Med Chem. 2008 May 15;16(10):5452-64. Epub 2008 Apr 11. PMID:18434170 doi:10.1016/j.bmc.2008.04.010
Page seeded by OCA on Wed Feb 18 09:29:12 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Phosphorylase
- Katayama, N.
- Onda, K.
- Acetylation
- Allosteric binding
- Allosteric enzyme
- Allosteric site
- Carbohydrate metabolism
- Disease mutation
- Glycogen metabolism
- Glycogen storage disease
- Glycosyltransferase
- Nucleotide-binding
- Phosphorylation
- Polymorphism
- Pyridoxal phosphate
- Transferase