3bg3 | pdb_00003bg3

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File:3bg3.png

Template:STRUCTURE 3bg3

Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus)

Template:ABSTRACT PUBMED 18297087

Disease

Known disease associated with this structure: Pyruvate carboxylase deficiency OMIM:[608786], Thrombophilia due to protein C deficiency, autosomal dominant OMIM:[612283], Thrombophilia due to protein C deficiency, autosomal recessive OMIM:[612283]

About this Structure

3BG3 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Xiang S, Tong L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat Struct Mol Biol. 2008 Mar;15(3):295-302. Epub 2008 Feb 24. PMID:18297087 doi:10.1038/nsmb.1393

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