2j5y | pdb_00002j5y
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CRYSTAL STRUCTURE OF THE GA MODULE FROM F.MAGNA
Overview
The albumin-binding domain, or GA module, of the peptostreptococcal, albumin-binding protein expressed in pathogenic strains of Finegoldia, magna is believed to be responsible for the virulence and increased growth, rate of these strains. Here we present the 1.4A crystal structure of this, domain, and compare it with the crystal structure of the GA-albumin, complex. An analysis of protein-protein interactions in the two crystals, and the presence of multimeric GA species in solution, indicate the GA, module is "sticky", and is capable of forming contacts with a range of, protein surfaces. This might lead to interactions with different host, proteins.
About this Structure
2J5Y is a Single protein structure of sequence from Finegoldia magna. Full crystallographic information is available from OCA.
Reference
Crystal structure of a bacterial albumin-binding domain at 1.4A resolution., Cramer JF, Nordberg PA, Hajdu J, Lejon S, FEBS Lett. 2007 Aug 10;581(17):3178-82. Epub 2007 Jun 12. PMID:17575979
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