3gcw | pdb_00003gcw

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File:3gcw.jpg

Template:STRUCTURE 3gcw

PCSK9:EGFA(H306Y)

Template:ABSTRACT PUBMED 19224862

Disease

Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[606945]

About this Structure

3GCW is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. McNutt MC, Kwon HJ, Chen C, Chen JR, Horton JD, Lagace TA. Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells. J Biol Chem. 2009 Apr 17;284(16):10561-70. Epub 2009 Feb 17. PMID:19224862 doi:10.1074/jbc.M808802200

Page seeded by OCA on Wed Mar 4 15:04:03 2009

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