2uue | pdb_00002uue
From Proteopedia
REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS
Template:ABSTRACT PUBMED 17051658
About this Structure
2UUE is a 6 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 2c5t. Full crystallographic information is available from OCA.
Reference
- Andrews MJ, Kontopidis G, McInnes C, Plater A, Innes L, Cowan A, Jewsbury P, Fischer PM. REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors. Chembiochem. 2006 Dec;7(12):1909-15. PMID:17051658 doi:10.1002/cbic.200600189
- Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:https://dx.doi.org/10.1016/j.chembiol.2005.11.011
Page seeded by OCA on Wed Mar 25 12:56:57 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Andrews, M J.
- Cowan, A.
- Fischer, P M.
- Innes, L.
- Jewsbury, P.
- Kontopidis, G.
- Mcinnes, C.
- Plater, A.
- Active
- Atp-binding
- Cdk2
- Cell cycle
- Cell division
- Cyclin
- Cyclin groove
- Inhibition
- Kinase
- Mitosis
- Nonpeptide
- Nucleotide-binding
- Phosphorylation
- Polymorphism
- Serine/threonine-protein kinase
- Transferase
