3eoa | pdb_00003eoa

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Template:STRUCTURE 3eoa

File:3eoa.jpg

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I

Template:ABSTRACT PUBMED 19258452

About this Structure

3EOA is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Li S, Wang H, Peng B, Zhang M, Zhang D, Hou S, Guo Y, Ding J. Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4349-54. Epub 2009 Mar 3. PMID:19258452

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