2pnf | pdb_00002pnf
Structure of Aquifex Aeolicus FabG 3-oxoacyl-(acyl-carrier protein) reductase
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Overview
The gene product of fabG from Aquifex aeolicus has been heterologously, expressed in Escherichia coli. Purification of the protein took place, using anion-exchange and size-exclusion chromatography and the protein was, then crystallized. Diffraction data were collected to a maximum resolution, of 1.8 A and the initial phases were determined by molecular replacement., The A. aeolicus FabG protein is a putative beta-ketoacyl-acyl carrier, protein reductase. Structure-function studies of this protein are being, performed as part of a larger project investigating naturally occurring, deviations from highly conserved residues within the short-chain, oxidoreductase (SCOR) family.
About this Structure
2PNF is a Single protein structure of sequence from Aquifex aeolicus with 1PE and MES as ligands. Active as [acyl-carrier-protein_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number 1.1.1.100 Full crystallographic information is available from OCA.
Reference
Crystallization and X-ray diffraction analysis of the beta-ketoacyl-acyl carrier protein reductase FabG from Aquifex aeolicus VF5., Mao Q, Duax WL, Umland TC, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt, 2):106-9. Epub 2007 Jan 17. PMID:17277451 [[Category: 3-oxoacyl-[acyl-carrier-protein] reductase]]
Page seeded by OCA on Wed Nov 21 13:36:09 2007
