3gxp | pdb_00003gxp

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File:3gxp.jpg

Template:STRUCTURE 3gxp

Crystal structure of acid-alpha-galactosidase A complexed with galactose at pH 4.5

Template:ABSTRACT PUBMED 19374450

Disease

Known disease associated with this structure: Fabry disease OMIM:[300644], Fabry disease, cardiac variant OMIM:[300644]

About this Structure

3GXP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lieberman RL, D'aquino JA, Ringe D, Petsko GA. Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability. Biochemistry. 2009 May 1. PMID:19374450 doi:https://dx.doi.org/10.1021/bi9002265

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