Sandbox1988

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In Professor Sun’s guest lecture, he discusses the usefulness of using quorum-sensing and the applications it has to determining cell density, diffusion and efficiency. 1upg is a system that is controlled by quorum-sensing, working to relocate plasmids containing tumor-inducers into the protein. By transferring these plasmids to 1upg, it allows the ‘bacteria to synchronize infection’ when the sensing cells have become involved. 1upg is comprised of a 2-chain structure, and has a cluster of 3 ligand sites within the protein. When a look is taken at the backbone structure, we see that very little of the molecule disappears, showing us that the structure is fairly simple and not complex. We also can see that the changed areas of the molecules is standard to that of normal proteins, where the charged areas are placed on the outer structure of the protiein, where it can interact with water.

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D load='1upg' size='350' frame='false' scene=
1upg, resolution 1.80Å (default scene)
Non-Standard Residues:	MSE
Related:	1us6
Structural annotation: Resources: InterPro : Ipr015309 Pfam : PF09228 SCOP : d1upga_, d1upgb_ UniProt : Q57471
Functional annotation: Biological process: regulation of transcription, DNA-dependent transcription conjugation
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml