3gxt | pdb_00003gxt

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Template:STRUCTURE 3gxt

File:3gxt.jpg

Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin

Template:ABSTRACT PUBMED 19374450

Disease

Known disease associated with this structure: Fabry disease OMIM:[300644], Fabry disease, cardiac variant OMIM:[300644]

About this Structure

3GXT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lieberman RL, D'aquino JA, Ringe D, Petsko GA. Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability. Biochemistry. 2009 May 1. PMID:19374450 doi:https://dx.doi.org/10.1021/bi9002265

Page seeded by OCA on Wed May 27 15:22:49 2009

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