3g42 | pdb_00003g42
From Proteopedia
Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor
Template:ABSTRACT PUBMED 19410464
About this Structure
3G42 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Park K, Gopalsamy A, Aplasca A, Ellingboe JW, Xu W, Zhang Y, Levin JI. Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem. 2009 Jun 1;17(11):3857-65. Epub 2009 Apr 22. PMID:19410464 doi:10.1016/j.bmc.2009.04.033
Page seeded by OCA on Wed Jun 3 10:07:56 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- ADAM 17 endopeptidase
- Homo sapiens
- Aplasca, A.
- Gopalsamy, A.
- K., Park.
- Levin, J I.
- Xu, W.
- Zhang, Y H.
- Alternative splicing
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Polymorphism
- Protease
- Sh3-binding
- Tace-inhibitor complex
- Tace/adam-17
- Transmembrane
- Zinc
- Zn-endopeptidase
- Zymogen
