3fxi | pdb_00003fxi

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File:3fxi.png

Template:STRUCTURE 3fxi

Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex

Template:ABSTRACT PUBMED 19252480

Disease

Known disease associated with this structure: Endotoxin hyporesponsiveness OMIM:[603030], Colorectal cancer, susceptibility to OMIM:[603030], Longevity, susceptibility to OMIM:[603030], Macular degeneration, age-related, 10 OMIM:[603030]

About this Structure

3FXI is a 4 chains structure of sequences from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30;458(7242):1191-5. Epub 2009 Mar 1. PMID:19252480 doi:10.1038/nature07830

Page seeded by OCA on Wed Jun 10 22:12:40 2009

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