3eb1 | pdb_00003eb1

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File:3eb1.jpg

Template:STRUCTURE 3eb1

Crystal structure PTP1B complex with small molecule inhibitor LZP-25

Template:ABSTRACT PUBMED 19012396

About this Structure

3EB1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Liu S, Zeng LF, Wu L, Yu X, Xue T, Gunawan AM, Long YQ, Zhang ZY. Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J Am Chem Soc. 2008 Dec 17;130(50):17075-84. PMID:19012396 doi:10.1021/ja8068177

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