3ee0 | pdb_00003ee0
From Proteopedia
Crystal Structure of the W215A/E217A Mutant of Human Thrombin (space group P2(1)2(1)2(1))
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3EE0 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:https://dx.doi.org/10.1074/jbc.M407272200
Page seeded by OCA on Wed Jul 8 12:40:45 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Thrombin
- Bush-Pelc, L.
- Cera, E Di.
- Chen, Z.
- Gandhi, P S.
- Page, M J.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Pharmaceutical
- Polymorphism
- Protease
- Secreted
- Serine protease
- Zymogen
