2wcx | pdb_00002wcx
From Proteopedia
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS
About this Structure
2WCX is a 1 chain structure of sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Di Marco S, Volpari C, Tomei L, Altamura S, Harper S, Narjes F, Koch U, Rowley M, De Francesco R, Migliaccio G, Carfi A. Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site. J Biol Chem. 2005 Aug 19;280(33):29765-70. Epub 2005 Jun 13. PMID:15955819 doi:https://dx.doi.org/10.1074/jbc.M505423200
Page seeded by OCA on Wed Aug 19 13:20:42 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Hepatitis c virus
- RNA-directed RNA polymerase
- Marco, S Di.
- Allosteric inhibitor
- Atp-binding
- Envelope protein
- Genotype 1b
- Hcv
- Helicase
- Hydrolase
- Membrane
- Nni
- Non nucleoside inhibitor
- Ns5b
- Nucleotide-binding
- Polymerase
- Rna replication
- Rna-binding
- Rna-dependent rna-polymerase
- Transmembrane
- Viral protein
