3hx2 | pdb_00003hx2
From Proteopedia
Crystal structure of human ferritin Phe167SerfsX26 mutant. This file is a part 1/3 of the split entry and contains the copies 1 and 2 of the total six copies of the biological unit that are present in the crystallographic asymmetric unit. The entire structure contains six copies of the biological unit in the crystallographic asymmetric unit and is described in remark 400
Disease
Known disease associated with this structure: Basal ganglia disease, adult-onset OMIM:[134790], Hyperferritinemia-cataract syndrome OMIM:[134790]
About this Structure
3HX2 is a 48 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Baraibar MA, Barbeito AG, Muhoberac BB, Vidal R. Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration. J Biol Chem. 2008 Nov 14;283(46):31679-89. Epub 2008 Aug 28. PMID:18755684 doi:10.1074/jbc.M805532200
Page seeded by OCA on Wed Aug 19 13:40:27 2009
